CHANGE IN THE STRUCTURE AND PROPERTIES OF BLOOD CELL MEMBRANES AS A RESULT OF TEMPERATURE ACTION

A study has been made of the structure and properties of erythrocyte and thrombocyte membranes in patients with diabetes mellitus type 2 by the atomic-force-microscopy method. The infl uence of the temperature and the incubation time on the local mechanical properties of blood cells and the aggregation properties of erythrocytes has been assessed. The critical temperature and the incubation time for erythrocytes have been established, at which irreversible changes in the properties of erythrocyte membranes occur. It has been shown that thrombocytes are characterized by the higher thermally stable local mechanical properties of the membrane than erythrocytes.
   
Author:  G. B. Mel′nikova, T. N. Tolstaya, A. S. Petrovskaya, O. N. Shishko, E. É. Konstantinova, S. A. Chizhik, and T. V. Mokhort
Keywords:  atomic-force microscopy, local mechanic properties, erythrocyte sedimentation rate, erythrocytes, thrombocytes, temperature
Page:  1612